MMS Government Arts and Science College Malayinkeezhu was established in the name of famous poet, Madhava Panicker in 2014. The first Bhagavat Gita that Malayalam language received is through Madhava Panicker. Madhava Panicker came to Malayinkeezhu as part of some temple related activities and he was captivated by the scenic beauty of this place. Thus he gradually became a permanent resident of this area. While residing here, he became engaged in literary works.

It was considered that (Jananappanuval) Bhaasshabhagavatgita was written on the blessing of Thiruvallabha and is counted as the noblest among the translation of Gita. The poet had pictured Malayinkeezhu equal to Amaravathy. Without losing its originality and meaning it had been summarized and translated to 328 stanzas. This is today considered as the first translation of Gita. Among the Kannasa trio, Malayinkeezhu Madhava Panicker stands unique as a polestar in Malayalam literature.

Taking into consideration the significance of this place, the then Government of Kerala decided to start a college here and was named after this rate poetic genius. Accordingly the college was established as per G.O (MS) No. 641/13/H.Edn. Thiruvananthapuram dated 15/10/2013. As per GO (MS) No. 128/2014/RD Thiruvananthapuram dated 01/03/2014 five acres of land (3.90 acres belonging to Govt. VHSS and 1.10 acres belonging to Govt. GHSS) comprised in Block No. 6, Sy. No. 6/7 situated in Malayinkeezhu Village of Kattakkada Taluk in Thiruvananthapuram District was taken from General Education Department and hander over to Collegiate Education Department at free of cost to set up the Government Arts and Science College Malayinkeezhu, Thiruvananthapuram.

The college started its functions in 2014 with three degree courses – BA English, B.Com and B.Sc Mathematics. In 2020, a PG course – M.Com was also started. The College is affiliated to University of Kerala as per Order No. Ac.B/03/NC/2013-14 Dated 20/05/2014 of the Registrar, University of Kerala. During the academic year 2022-23 the College has 387 students and 33 staff members (both teaching and non-teaching). The college now is in the path of progress.